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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22c42e2b5f571a677942f77329002a49002ac4fa329840f57db1aa99a8e4d69' 
  AND token = 'XyYlNkAK9+cjoCsaUFVOL9lowWYMzSnE2N7meEAvMSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}