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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b15734ffcfc4f3be5446019d7dc53049e66936ceee7fe9503a3afb597a7e5f44' 
  AND token = '4F1L74vwenxsxMSkrlt5PL8S8BIw5Qt7Zn7pZ7DjrTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}