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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a929a3a7d2800427f4126996c2b2616a1d437937bb719ac906fa705060af657' 
  AND token = 'XDIAzf287ELtWpkiF8L2yefXE9rbjFYWKN6c/yOmgpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}