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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb0786857c06a4470d6dec960a5fc795bc3fdc0b7757d1bc44f0a39df03f57da' 
  AND token = 'B1t/0VMAr9cfFaCDL/Qp1ijPKciDr0R/B95oE1sf5xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}