SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f71b8dfaa816fd2cdfb1e9d110b29d5a2830ada0c7cf52c3fd2d2965fee31c14' 
  AND token = '9EOdLFJhERUJD/1RJYsaiGmASWrJQqv8uby9kWlqV/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}