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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ed7ff68a79db348f642a7228159123d978d3ff3ce01b9735cb4b68097acbd5' 
  AND token = '6cplVQcFzhfM9KBZhZ0uteX1b4lUfXPiN85tGtAE+yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}