SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9923dcbb2798a798bd5cd21f60a6ed9bc1874bffc7d642115ed458d1c56452' 
  AND token = 'A7D2nJn9dNhpXnySlbJZFVeQM7n9qwqGzVXSDl0q47E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}