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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf7605529bdd2928a621d1804f64127681eae314475ddb85d2e305aab0b8ad7' 
  AND token = 'Py7HDlVpPD0EkwkRpmFCCJPHfGJjq1CWe86ZWQRBQsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}