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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fca36d744f09d45aaf3cb2054780497b9143f03c274bf272ec81f466d3edfea1' 
  AND token = 'J+TB1fJ9Ix3MzykwcbkxneknCzyM2kM9npiNfk+XOWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}