SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86d5f90bacc40878c6ee4e8a7107c08e9143cd7b532f232291772e575365cdd1' 
  AND token = 'x0GVYcsuAtvtQGTwjTwbOe+Q4EKNG6kkv7qNj4MpCf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}