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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e60eeb416387c552a5523f6abda2bac86f18e842cc882846c2718eef4a20f724' 
  AND token = 'Ax/ZvtUWYfxXLxFRdRGNgkNmaet1pa44DOO6AienvSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}