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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b2f09c331d78effd8ad8d0a33d818510e70065813fa80091cd38ef03a2f6f9' 
  AND token = 'N141w5zM29VIKpRKrQbie9VNc8Vk6Xqy7B4BiA9+JEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}