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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eceb9b7658e8b15bf642134806877cb79ef5d3516921329f336d122afeeaef93' 
  AND token = 'zV5rTwaDJ51S1gtaz/PUPMTej4SDgemdzerRd2tIWl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}