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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bc8656f6e25bd89b1bc3d687a9ceff105c787debcccd52d205f7984f0d4c51f' 
  AND token = 'AUH2h0r2bOOOQLNLhJObC1GHF4+WO3YAQuaojUz0MHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}