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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486570b64fa2c8b5b166fc5683c12b712f27b76d2a8b0ce091e1ffc2c4824161' 
  AND token = 'aGH4srInD86oskLc2Tk2RZg7b16hMMNJkDmpoqyItmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}