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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97c54a5b5192f2885b7816912aaeb125304882016398ec5f9507562e3c4c72bd' 
  AND token = 'M0Pg+ZjEbqCy98GW2KAYAyg6kjeHVicuVz2YQ4TMQeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}