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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7297b84720c9616e1cb72f1f67ffb0198cc7dc992b88f2741d157e350571813a' 
  AND token = '8R8DrKSr2rz7BW0F/ewx0q7PwjR/14uo2yxDi0ROQ1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}