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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca372089225c3fd18bda040e3c1e2ae52ab9da22345322bfcbb0686491d67f8' 
  AND token = '/s4X7VnXC1XZ3cX+eMRzfBIfI56cDNA5NW670gF85CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}