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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27da9c9746ac6f08d328f6e68f05fbf0098975b2da7a60ec725d64f6bf9d391' 
  AND token = 'pNW/PZbTgToBoULWv/r9CsK1eLQ2bkrVoL+JIXXr3ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}