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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9434ceb009e3191800abed4aad52212583120feb0991773eb7a4a317a8c97ac' 
  AND token = '54O02UN75Qara+AY5BCmDmoOk0YSnfFjUQDzkNHdY0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}