SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47176072921c7fb26e11fcbf9ab2efd92b85abb08b5d5bf21aa47e2756bb6c13' 
  AND token = 'aI9UpQIzAu1v+D0nOuLqrVmWaK85vW0CBdWRcXxJXM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}