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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd885d606f2df3f128e5ff2db8cd12d4eb52b37b06bdad05c8d6db5525c0a0ec' 
  AND token = 'FklK0NMyuYuVPh/Gt+gmaHqEsSFnFAfmCEZy9yKeLls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}