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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4ea2146f2338eb3e3f37b18dd63e727c3a7a8fcbf7edc0a18457ec746b9484' 
  AND token = '1ro7Qd4T6zpU/p2AER3/nGmFNxPosuBhCPXaZNEIb3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}