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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e2e81b48d1ca3348ef560046774d5b8681422553b30508ae0b1aefdaa705fd' 
  AND token = 'mh3/o4o3HdlwmhPbdsJMLF8/T1pFM5K0GDuYwL2wCrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}