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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55e36bc8e5b574a25090a351f79ec17f86219412d701d8872916975e7237c403' 
  AND token = 'vmx/w9YNLt40zJV+Jy5b7AM+/1lSmMEFlv6h2+mqck0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}