SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad417fb124addcd22ef71be513ac4c9e8f3bb9c0af6616adddbab56bedbbafa4' 
  AND token = 'pioLasUq+oM2t1E8RPgsV4GWLLPZSOI6jhXZYLwv3Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}