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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dbd53cfb35346d0a0ace70b652cc5c00c79275f2054ea7825c1531e0c186191' 
  AND token = 'lzGxfUbbNK/2ePs61sx6NUJ3Ek3F3KYUgOs2a5BYgDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}