SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5b25b0fdf21a68ea10a556bc35b503ebc06f5dfff7319d23bc79ff0062b1e16' 
  AND token = 'r1cXSH/btERNfbQqFiPEaDquP+BGCg4KM2wI8Dj279k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}