SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5383f1789693c4150e934749feef948d909fa5f136cb20442fb66f8b8514260' 
  AND token = 'zbA3OaxMLVJYQcXBqpuTJZp5SL066zoFUOa/ZEIJ+hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}