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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08150b4530f3fddc23c323f5e8042408306c31620aedda428f4740601e391e5' 
  AND token = '/SY6mS38Ll15xPxTcZwXp+jp0hlEOPMz9Bpw335KRnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}