SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ea55c8fb479d9b83759ab24113a2212b950bd18b28e104cf63e40c7e049456' 
  AND token = 'obga9Vu1ACjd0faUl8UZy5LNyl8aSGYW40TpzVudVcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}