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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b6e7a9050dcd096eb3a98c1376f3933ab1cc9dadddb8786d19735f38794eef' 
  AND token = '+uQ2j8EeeX9RJZzu7XNE4Hc/vIGph0BoQbCWHg4299c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}