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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2460c2b2791abb5e7195b5ac0cef3bce3bfb9487c880558629eee2ba1e99be3b' 
  AND token = 'XGfKUUWoE0fyKq0LP5YmRYZfOxzG6lfPn8k5a3naEGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}