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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9906d993ba820e573cac5522907e21fb6057c40b3981ffbdc735d0783c73ee3b' 
  AND token = 'PpR95H0J+sw8T/cs/2KekKkb+tObbXTT+0MltFVRwzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}