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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b992aabf3f2e063de2b9be49c75afc11fb2286879f956673295a522b1b39b5' 
  AND token = '7gwQ1/oO2cjn/5cK1pDmrloM7BEmr48b5NZu6DF8Cck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}