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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ddb4c200c8debc1c68ee48d438560178db746cb4ceff27736aa88d5a207b22' 
  AND token = 'TALTF6gFHxHOCR4JLIxMYZJgOa1QKjrdIUQNQ9q8nIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}