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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a66ffaa3d70ac10dff44f0bd5e3150b0cf1b9429e9292c1689ffba0c901e6e2' 
  AND token = 'vISdW9NJQfv1JTUWc+kElpuvGFOkqpOYZdY2SV7rClQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}