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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6406e3c625774ada1ca10e122c45d14a9a0d1b9a4e01fb9c461b2a9ae31ef4d1' 
  AND token = 'STNXanv0vPNFbURM/iYEioAtH8fVCU076mCttmseSsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}