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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a109ad8587820f4060abc75b96d476fe84ad18522af618a366c45e09a34b03a5' 
  AND token = 'z3a+ZwrXjpwx9oriaWtnmU3IZL4pQO6ovzxjFim+X/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}