SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0740b09ec6f030dbcc7d496ba4ba5199c21fd65663ed3443c0ac1579e0ba1d82' 
  AND token = '7mqBJAVU0C1tMKMinJvWC1S1BGSGShU7nwFDB8hntzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}