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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550728cbbbdcc9764b0aa7013f3476d924eea3ceb50dccce09d93d1e1eb380b1' 
  AND token = 'cxbokSlv6p6Pa1wqQfjU+RRe54wC5tsQRuVVw26zMyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}