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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72497b2a73ac63d683713e9f97257eedd967ee4c492b566ec6de604fff8a1c3b' 
  AND token = 'es1XSxkHapZZQ9Qrwiatk35zCDKPEZQR4p+THkfPl7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}