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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae5a29951fcf5e77b0fab27f36124bdf2a76fab1e1b4c970c00ca47c1402e640' 
  AND token = 'by/td2AbhSYioeXoRTj5BipRmBTx8FYHrUkmLeo3WsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}