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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d177b34e8d7e113bfa611d453828836989939ac6f9093e9e0a182d7866d764' 
  AND token = '853xr2OUi5rxLpxkvRMT+9M8JAjGyQY+1v7BNtMvQ94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}