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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3742001f663ef5db7602d660394a92ac0bf8f258ef9ddd2ffd2b79362f7cd072' 
  AND token = '1E27Z3AhG4xZDO+4mifpOGD3/ARwGUUfdYJmmiU5ne8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}