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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d415e6e6867a8cd9306c04dc8fc9343e868df3ec949cd4e701bd67916c79c75' 
  AND token = '6p0MndWrVrgRdwxSaTYq6ip8apws0FMu8A4/DiS6YMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}