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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1f9adce4cf4a93b98bfeea37d88af400290d010cbe58f637ed0a3240da1cdf' 
  AND token = 'hrch9HjxqcRGRTSNj4O53d2uLo/3uy9nPCiJkq+yxlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}