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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f8e6f4cb5767a22b9b9c729c5c4069e334954a12f5f4fc11cb241e9b1cc526' 
  AND token = 'GU4l+qAusLPr1Y6vh4fpCX1MhKN9Oq9HJ2zVYN3+7IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}