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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a22cd46ccf9bf9caf054e259614ec9559a552be8c359263c18ff9d9952ee925' 
  AND token = 'iqMVdjU+TS+2scDz130NQimlDnkIqTw0OcE8SnlrFPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}