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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b651f35a644209a05dc9f8440b38a3e53f6fd8fe28c157ac3a5980857f48f966' 
  AND token = 'qxXgEBx6bZAn3XTLkbaS5pblGuVk8LzN1GfFRHLit5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}